The Histofreezer products are only sold through Medical/Surgical distributors. Please contact our Customer Care Department (support@cryoconcepts.com) for help locating an authorized distributor in your area.

60M2C+10 VALUE KIT

• 70-140 applications per kit^*
• (24) 2mm and (46) 5mm applicators
• Up to three-year shelf-life
• Ideal for high volume practices

36M1C STARTER KIT

• 36-72 applications per kit^*
• (12) 2mm and (24) 5mm applicators
• Up to three-year shelf-life
• Ideal for small and large lesions

36F1C 5MM SPECIALTY KIT

• 36-72 applications per kit^*
• (36) 5mm applicators
• Up to three-year shelf-life
• Ideal for treatment of larger lesions and plantar warts

40T1C 2MM SPECIALTY KIT

• 40-80 applications per kit^*
• (40) 2mm applicators
• Up to three-year shelf-life
• Ideal for treatment of smaller lesions

^*See  Package Insert for more information

Yes.  Click here to print Cryotherapy-Histofreezer Patient Guide.

Verruca vulgaris (Common warts)

A common wart of the skin or mucosa. The warts are round firm skin-colored papules with a hyperkeratotic (thickening) papillary surface. Sizes range between 1 to 10 mm. The hands, fingers and knees are common sites. Thrombosed capillaries which appear as black dots can be seen on the surface of some warts.

Verruca plantaris (Plantar warts)

Painful, unappealing benign tumors on the sole of the feet caused by the Human Papillomavirus (HPV-1) when it enters the skin through a cut or skin erosion. These warts can generally be characterized as rough, round-oval growths that can be lighter or darker than their surroundings.

Verruca plana

Also known as a “flat wart”, round or oval shaped, only slightly elevated and sharply defined. They may induce however significant disturbances of pigmentation anywhere from flesh-colored in appearance to dark brown. Auto inoculation by scratching can result in linearly grouped lesions. Location of these lesions is commonly found on the forehead, cheeks, perioral (tissues around the mouth) as well as the dorsal side of hands and arms.

Molluscum contagiosum

A contagious disease of the skin caused by intranuclear proliferation of a virus of the family Poxviridae and characterized by the appearance of small,pearly, umbilicated papular epidermal growths. In adults it typically occurs on or near the genitals and is sexually transmitted.

Acrochordon

Common benign skin growths (a/k/a skin tags) that occur most often after midlife. They are tiny skin protrusions, and may have a small narrow stalk connecting the skin bump to the surface of the skin. The origin is unknown however is believed to be an inherited indication.

Actinic keratosis

A premalignant warty lesion occurring on the sun-exposed skin of the face or hands in aged light-skinned persons; hyperkeratosis may form a cutaneous horn, and squamous cell carcinoma of low-grade malignancy may develop in a small proportion of untreated patients.

Lentigo

A brown macule resembling a freckle except that the border is usually regular, and microscopic proliferation of rete ridges is present; scattered melanocytes are seen in the basal cell layer.

Seborrheic keratosis

Superficial, benign, verrucous, often pigmented, greasy lesions consisting of proliferating epidermal cells, resembling basal cells,enclosing horn cysts; they usually occur after the third decade.

Condyloma acuminata

A warty growth on the external genitals or at the anus, consisting of fibrous overgrowths covered by thickened epithelium showing koilocytosis,due to sexually transmitted infection with human papilloma virus; malignant change is associated with particular types of the virus.

Note: Refer to the Histofreezer  Package Insert for the lesion-specific treatment times.

Lesions are resolved in one to four treatments with two-week intervals between treatments.

The Histofreezer products have a shelf life of five years from the date of manufacture. Though the need is unlikely, this means there is sufficient cryogen in each canister on the expiration date to saturate all of the Histofreezer applicators provided in a kit.

A study showed an average rate of 93.4% effectiveness for a variety of lesions.¹

After saturation of a 5mm Histofreezer applicator, you may perform a second application on the same patient after a 15-second pause between applications. The use time of a saturated 5mm Histofreezer applicator is 120 seconds.

After saturation of a 2mm Histofreezer applicator, you may perform a second application on the same patient after a 15-second pause between applications.The use time of a saturated 2mm Histofreezer applicator is 90 seconds.

Note: Refer to the Histofreezer  Package Insert for the lesion-specific treatment times.

The applicator temperature reaches -55°C, which minimizes risk of scarring or blistering of the treatment site.

Do not use a used applicator for another patient due to risk of cross-contamination. A sufficient supply of applicators is included with each kit.

No. Histofreezer has been approved for external condyloma lesions only. This would include any condyloma for anogenital, labial and penile lesions.

The Dimethyl Ether, Propane, and Isobutane gas in the Histofreezer canister is a clear liquefied gas that is not harmful to clothing or furniture. Any drips that occur can be simply washed off with a mild soap and will not leave any stains.